{"id":14892,"date":"2020-12-02T19:05:32","date_gmt":"2020-12-02T06:05:32","guid":{"rendered":"https:\/\/clladvocates.nz\/?p=14892"},"modified":"2020-12-02T19:05:32","modified_gmt":"2020-12-02T06:05:32","slug":"case-study-covid-19-and-the-coexistence-of-cll","status":"publish","type":"post","link":"https:\/\/clladvocates.nz\/?p=14892","title":{"rendered":"Case Study: COVID-19 and the Coexistence of CLL"},"content":{"rendered":"

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Case Study: COVID-19 and the Coexistence of CLL<\/h1>\n

[\/vc_custom_heading][vc_column_text]This article was originally published on Docwire News\u00a0<\/a><\/p>\n

Many symptoms of SARS-CoV-2 (COVID-19) can be concealed due the coexistence of malignant hemopathies such as chronic lymphocytic leukemia (CLL), according to a case report published in\u00a0The Pan African Medical Journal<\/em>.<\/p>\n

In this case, an elderly man (76 years) who previously underwent surgery for colon cancer was admitted to intensive care for pneumonia.\u00a0The patient presented with a dry cough, very high fever (104<\/em>\u00b0F), swollen lymph nodes, and diarrhea.\u00a0<\/em>A polymerase chain reaction test was conducted and came back positive for COVID-19. A chest CT scan showed pulmonary opacities with consolidation. During his admission, the authors noted that the patient was conscious and breathing 85% at room air with intercostal retraction, with stable hemodynamics: blood pressure, 140\/75mmHg; heart rate, 90 bpm; and 39\u00b0C fever. Electrocardiogram showed normal sinus rhythm, fixed duration of PR interval, and QTc at 475. Transthoracic echocardiography was normal, they added.<\/p>\n

Lab tests conducted on his first day of admission showed the following: elevated white blood cell count at 140020el\/mm3<\/sup>\u00a0and lymphocytes 129660el\/mm3<\/sup>\u00a0(vs. 154000el\/mm3<\/sup>\u00a0at D7), low hemoglobin at 8.9 g\/dL, platelets at 464000el\/mm3<\/sup>, prothrombin time at 64%, fibrinogen at 6.77 g\/L, C-reactive protein at 130 mg\/L, brain natriuretic peptide at 249 pcg\/L, procalcitonin at 0.017 \u03bcg\/L, LDH at 331 UI\/L, ferritin at 563 \u03bcg\/L, and troponin at 8.2 ng\/L. A blood smeared displayed small lymphocytes with rounded nucleus and reduced cytoplasm. The patient was treated with four daily noninvasive ventilation sessions, hydroxychloroquine (200 mg, twice a day), azithromycin (500 mg\/day), ceftriaxone (2 g\/day) and moxifloxacin (400 mg twice a day), human immunoglobulins (0.5 g\/kg single dose), anticoagulation, proton pump inhibitor, vitamin C, vitamin D, and zinc.<\/p>\n

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Many symptoms of SARS-CoV-2 (COVID-19) can be concealed due the coexistence of malignant hemopathies such as chronic lymphocytic leukemia (CLL),<\/p>\n","protected":false},"author":1,"featured_media":14893,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"_jetpack_memberships_contains_paid_content":false,"footnotes":""},"categories":[17,22,23],"tags":[],"class_list":["post-14892","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-featured","category-covid19","category-research"],"jetpack_featured_media_url":"https:\/\/clladvocates.nz\/wp-content\/uploads\/2020\/12\/COVID-1902-12-20-e1645857282596.png","jetpack_sharing_enabled":true,"_links":{"self":[{"href":"https:\/\/clladvocates.nz\/index.php?rest_route=\/wp\/v2\/posts\/14892","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/clladvocates.nz\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/clladvocates.nz\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/clladvocates.nz\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/clladvocates.nz\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=14892"}],"version-history":[{"count":1,"href":"https:\/\/clladvocates.nz\/index.php?rest_route=\/wp\/v2\/posts\/14892\/revisions"}],"predecessor-version":[{"id":14894,"href":"https:\/\/clladvocates.nz\/index.php?rest_route=\/wp\/v2\/posts\/14892\/revisions\/14894"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/clladvocates.nz\/index.php?rest_route=\/wp\/v2\/media\/14893"}],"wp:attachment":[{"href":"https:\/\/clladvocates.nz\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=14892"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/clladvocates.nz\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=14892"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/clladvocates.nz\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=14892"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}