Treatment Pathways for Active CLL

This is the second in a series of slides from the recent CLL conference in Edinburgh that may be of interest to CLL patients.

This summarises current treatment options for active CLL and lists risk factors that would influence treatment decisions.

Abbreviations:

CIT = chemoimmunotherapy, eg FCR (fludarabine, cyclophosphamide, rituximab)

Allo SCT = allogeneic stem cell transplant with stem cells from another matching person – related or unrelated. In practical terms, it is uncommonly done, can cause GVH (graft versus host disease), and is recognised as a potential cure for CLL .

MRD = minimal residual disease, ie remission.