Clinical trials

This page is designed to help you find clinical trials that may suit your needs. We hope that this additional information will make it easier to discover and access trials relevant to your medical condition.

Clinical trials can provide access to innovative treatments and serve as alternatives when standard options are not suitable. By offering a centralised resource, CLL Advocates aims to streamline the search process for patients, making trial opportunities more accessible and user-friendly.

To find a clinical trial that may be suitable for you, you can refer to the spreadsheet of available trials and follow these steps:

  1. Click here to review the Spreadsheet: Start by reviewing the clinical trials listed in the spreadsheet, focusing on details such as the trial’s purpose, location, and treatment options.
  2. Check Eligibility Criteria: Each clinical trial will have specific eligibility requirements, such as the type and stage of cancer, age, previous treatments, and overall health status.
  3. Consult with your doctor: You should discuss your interest in the clinical trial with your doctor or specialist. The healthcare provider can assess whether you would make a suitable candidate for available trials.
  4. Location and Accessibility: Check the trial locations and consider your ability to travel for participation. Some trials may require frequent visits, so geographic proximity and your mobility are important factors.
  5. Discuss Risks and Benefits: With the healthcare team, weigh the potential benefits of the trial treatments against the risks and side effects. This will help determine whether a particular trial is suitable for your health status and treatment goals.
  6. Reach Out for Further Information: Once a potential match is found, the patient or healthcare provider can contact the trial coordinator for additional information, such as how the trial will be conducted, timelines, and potential outcomes.

 The potential benefits:

Access to New Treatments: Clinical trials often provide access to experimental treatments that are not yet available through standard healthcare. For CLL patients, these treatments may include the latest targeted therapies, immunotherapies, or drug combinations. By the time drugs are being tested in Phase 3 randomised trials they have already been tested extensively in Phase 1 and 2 studies looking at safety and efficacy.

Potential for Better Outcomes: New therapies in trials are designed to improve treatment effectiveness, reduce side effects, or offer solutions when standard treatments no longer work.

Contributing to Research: By participating, patients contribute to the development of future treatments, helping improve care for others with CLL.

Safety and Ethical Standards: Clinical trials in New Zealand, as in other countries, are conducted under strict regulatory and ethical standards, ensuring that patient safety is a top priority.

Enhanced Care: Patients in trials often receive more frequent monitoring and care as part of the study, which can improve their overall treatment experience. There is evidence that taking part in a clinical trial improves outcomes even in those people who do not receive the new drug.

CLINICAL TRIALS

Trial I.D: BGB-11417-301 (Celestial)

  • Treatment: A Phase 3, Randomised Study
  • Patient Criteria: Treatment naïve & needing treatment
  • Locations: Wellington, Christchurch, Tauranga, North Shore.
  • Note: Open to those previously on the Celestial trial
  • Note: most available slots have been taken. Each case is being reviewed individually. Some places are available in centres that have recruited low numbers.
  • Study Type: Phase 3, Randomised Study
  • More Information: ClinicalTrials.gov – NCT06073821

Trial I.D: LOXO-BTK-20030

  • Treatment: A Phase 3, Randomised Study
  • Patient Criteria: All patients needing treatment
  • Locations: Dunedin, Waikato
  • Study Type: Phase 3, Randomised Study
  • More Information: ClinicalTrials.gov – NCT05254743

 

Trial I.D: AbbVie M14-728

  • Treatment: Phase 2 trial Participants with 17p deletion status will receive various doses of Venetoclax once daily
  • Patient Criteria: Relapsed/refractory CLL/SLL with 17p deletion
  • Location: Christchurch
  • Study Type: Participants with 17p deletion status will receive various doses of Venetoclax once daily
  • More Information: ClinicalTrials.gov – NCT02966756

 

Trail I.D: Bellwave 011

  • Treatment: A Phase 3, Randomised Study
  • Patient Criteria: Treatment-naïve; needing treatment
  • Locations: North Shore, Middlemore, Waikato
  • Study Type: Phase 3, Randomised Study
  • More Information: ClinicalTrials.gov – NCT06136559

 

Trial I.D: Rationale

    • Treatment: Phase 3 Clinician ALLG study
    • Patient Criteria: Patients with hypogammaglobulinaemia and recurrent infections
    • Location: Wellington
    • Study Type: Phase 3 Clinician ALLG study

The ClinTrial Refer has bridged a critical gap in clinical research, facilitating better knowledge management, and allowing more equitable access to clinical trials.

ClinTrial Refer supplies a current list of active and pending haematology clinical research trials in New Zealand updated monthly.

Designed for haematologists, research unit staff, general practitioners and patients. ClinTrial Refer has searchable clinical research trial details, hospital locations and contacts, and inclusion and exclusion criteria.

Use it to refer to trial sites and broaden patient access to clinical research studies. Filter by disease, hospital location, trial status and sponsor. Trial details allow the user to email or call participating trial units for further information and to refer a patient.

ClinTrial Refer is a project supported by the New Zealand Branch of HSANZ.

Download for iPhoneDownload for AndroidVisit the ClinTrial Refer website